Overexpression of PKD2 in the mouse is associated with renal tubulopathy
نویسندگان
چکیده
منابع مشابه
Overexpression of PKD2 in the mouse is associated with renal tubulopathy.
Polycystin-2 (PC-2), a cation channel of the Trp family, is involved in autosomal dominant polycystic kidney disease (ADPKD) type 2 (ADPKD2). This protein has recently been localized to the primary cilium where its channel function seems to be involved in a mechanosensory phenomenon. However, its biological function is not totally understood, especially in tubule formation. In the present paper...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2007
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfm763